Serum enzyme elevation in glutethimide intoxication.
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چکیده
منابع مشابه
Glutethimide and circulating 1,25-dihydroxyvitamin D in vitamin D intoxication.
Iqbal and Taylor used glutethimide to treat a patient with vitamin D2 intoxication, reasoning that induction of hepatic microsomal enzymes by the drug would result in more rapid catabolism of vitamin D metabolites. The treatment corrected the hypercalcaemia, and the raised serum total 25-hydroxyvitamin D concentration fell with induction of the enzymes, as indicated by a rise in y-glutamyltrans...
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Glutethimide concentrations were measured gas chromatographically in the serum and cerebrospinal fluid(CSF) of patientsincoma caused by overdose of thisdrug. Piperidionewas used as an internal standard.In the firstserum samples collectedfrom each patient,the glutethimideconcentrationranged from 0.9 to 3.1 mg/dl. No patient had a CSF glutethimideconcentrationof more than 0.8 mg/dI. If one exclud...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5725.751